One of the most progressive citizens of Ipswich, Dr. John Manning opened a practice in 1760, and began inoculating members of his family for smallpox, incurring the wrath of the Town. An epidemic of smallpox spread through Boston during the British occupation of the city at the beginning of the Revolutionary War.
In 1773, the selectmen ordered all houses where the disease had appeared to be closed, and dogs to be killed immediately. The fears of the inhabitants increased when permission was granted to build a smallpox hospital on Cat Island.
An estimated 18,000,000 Native Americans lived in North America before the 17th Century. The arrival of 102 Pilgrims aboard the Mayflower at Plymouth in 1620 and the settlements by the Puritans a decade later were accompanied by the demise of the native population of North America.
The frame of a 1692 house that once stood at the intersection of Manning and High Streets in Ipswich is on display in the “Art of the Americas” wing at the Boston’s Museum of Fine Arts.
Historic Ipswich 